Create accountLogin

Recent searches

No recent searches

Search options

Only available when logged in.
techhub.social is one of the many independent Mastodon servers you can use to participate in the fediverse.
A hub primarily for passionate technologists, but everyone is welcome

Administered by:

Server stats:

4.8K
active users

techhub.social: AboutStatusProfiles directoryPrivacy policy

Mastodon: AboutGet the appKeyboard shortcutsView source codev4.3.8

#Biome

0 posts0 participants0 posts today
Public
Howard Smith MD, AM

Improving Ovarian Cancer Immunotherapy: Cancer immunologists at the University of Virginia have now discovered what underlies this failure. #immunotherapy #checkpointinhibitor #ovarian #cancer #biome #flagellin
instagram.com/reel/DHDygk-shuL

InstagramHoward G. Smith MD, AM on Instagram: "Improving Ovarian Cancer Immunotherapy Immunotherapy has been a resounding success for melanoma skin cancer and small cell lung cancer. Not so for ovarian cancer. Cancer immunologists at the University of Virginia have now discovered what underlies this failure. Their research discovered that flagellin protein from gut bacteria blocks the effectiveness of the checkpoint inhibitors that power most current immunotherapy. This bacterial flagellin inhibits immune cell communication helping tumors flourish rather than die. Using a mouse model and blocking flagellin action restored immunotherapeutic effectiveness with 80% of treated animals enjoying long-term tumor control. If this approach is effective for human ovarian cancer patients, coupling flagellin blocking with checkpoint immunotherapy may be a winning therapeutic strategy …..someday soon. https://newsroom.uvahealth.com/2025/02/11/ovarian-cancer-discovery-could-turn-ailed-treatment-into-lifesaver/ https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-24-0513/751676/TLR5-signaling-causes-dendritic-cell-dysfunction?redirectedFrom=fulltext #immunotherapy #checkpointinhibitor #ovarian #cancer #biome #flagellin"3 likes, 0 comments - drhowardsmithreports on March 11, 2025: "Improving Ovarian Cancer Immunotherapy Immunotherapy has been a resounding success for melanoma skin cancer and small cell lung cancer. Not so for ovarian cancer. Cancer immunologists at the University of Virginia have now discovered what underlies this failure. Their research discovered that flagellin protein from gut bacteria blocks the effectiveness of the checkpoint inhibitors that power most current immunotherapy. This bacterial flagellin inhibits immune cell communication helping tumors flourish rather than die. Using a mouse model and blocking flagellin action restored immunotherapeutic effectiveness with 80% of treated animals enjoying long-term tumor control. If this approach is effective for human ovarian cancer patients, coupling flagellin blocking with checkpoint immunotherapy may be a winning therapeutic strategy …..someday soon. https://newsroom.uvahealth.com/2025/02/11/ovarian-cancer-discovery-could-turn-ailed-treatment-into-lifesaver/ https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-24-0513/751676/TLR5-signaling-causes-dendritic-cell-dysfunction?redirectedFrom=fulltext #immunotherapy #checkpointinhibitor #ovarian #cancer #biome #flagellin".
Public
Arend van Beelen

Another exciting #Biome development: I just opened a PR for our first **multi-file analysis rule: `noImportCycles`**

There is still some other tasks I need to do to complete the multi-file analysis, but hopefully this means we've also reached the point where contributors can chime in and implement the multi-file analysis rules that they couldn't before! And if not, please let us know what is still blocking you from implementing the rules you want! ❤️

github.com/biomejs/biome/pull/

Summary This PR adds a new rule: noImportCycles. Similar to the ESLint no-cycle rule: https://github.com/import-js/eslint-plugin-import/blob/main/docs/rules/no-cycle.md Also closes #4930 , because ...
GitHubfeat(lint): new rule: `noImportCycles` by arendjr · Pull Request #4948 · biomejs/biomeBy arendjr
Public
bundeskater

Weihnachten haben wir ein bisschen gemeinsame Zeit, die ist ja, wenn man in verschiedenen Städten lebt beschränkt.
Wir haben es für ein paar Erstpartien genutzt.
1.) Gemüsewürfel (Weihnachtsgeschenk) hat uns toll gefallen. Kurzweilig und toll mit dem Messer die Würfel abzutrennen. Hat in der ersten Partie überzeugt.

2.) Baumkronen / Canopy (Weihnachtsgeschenk). Thematisch gefällt es, aber so richtig überzeugen konnte es noch nicht.

3.) Lumicora (Weihnachtsgeschenk)
Thematisch super, ich mag jedes Unterwasserspiel, hat auch sonst überzeugen können

4.) Barcelona
Mir hat es sehr gut gefallen. Kommt bei mir öfter auf den Tisch

4.) Biome
Hat sofort begeistert. Gefällt uns beiden besser als Kavango. Wir bestimmt ein Dauerbrenner bei uns

5.) Raising Robots
Wer zur Hölle hat diese Anleitung geschrieben? Mit Videoanleitung war es dann recht verständlich.
Mir hat es sehr gut gefallen. Aber ob es Schwingenschlag schlägt? Es ist sehr kleinteilig. Flügelschlag liegt auf Grund der Thematik bei den dreien weiterhin vorne.
#brettspiele #boardgames #biome #raisingrobots #barcelona #lumicora#baumkronen

Spielbrett Raising Robots
Hasennest bei Biome
Lumicore Aufbau
Public *
anna_lillith 🇺🇦🌱🐖

Brazilian government: protect the Pantanal and STOP the waterway 🇧🇷

A massive industrial #waterway threatens the heart of the #Pantanal, the world’s largest #TropicalWetland. According to experts, the project could cause a shrinkage, increase the risk of catastrophic wildfires, and disrupt the #ecosystem beyond repair.

This #biome, which predominantly lies in #Brazil but also extends to #Bolivia and #Paraguay, is home to over 4,700 #species, many of which are endangered

1/7

ExploreLive feeds
About