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#microscopy

8 posts5 participants1 post today
Continued thread

Id want to keep the microscope and staining as an active part out of the game though. So you are not a microscopist who follows a single bacterium and applies different stains, because it would limit believably and realism if the game world would be only on a microscope slide.

The #staining and #imaging techniques would serve to bring across the magic of this hidden universe that becomes so vivid when you apply the right stains while also allowing for different game play tactics. I feel like there is nothing more wonderful and magical to see this world appear buzzing with life.

besides learning a lot about #microbiology and #microscopy #imaging i cant imagine anything more engaging and thrilling for a game.

You dont need to know anything about this stuff because if you see methods, principles and details of the micro physiology? in action they are easily understood and used.

I certainly dont have the programming skills to do this, besides waiting on the seed funding for my #startup anyway. But if i had the time and funding id love to do this. You could even go and make it an #mmorpg .

The whole game with its dynamics and vase skills / abilities is literally already there, it just need to be captured.
#gamedesign #science #research #biology

Continued thread

As you try to stay alive and evolve you decide a flagellum is the next best step to escape the certain death of an amoeba or maybe an endospore that while it wouldnt protect you from being eaten, it would be indigestible and allow you to survive an attack. Maybe later on you evolved to be able to attack other bacteria and have to decide if attacking a colony in front of you will be easy or if they might be dangerous to yourself.

Here come the different #imaging and #staining techniques in #microscopy into play.

Instead of what is typical in a #firstperson #shooter to switch to #nightvision or #thermalvision you switch between different staining methods to visualize all the hidden detail of this world.

You switch the visualization to a #negativestain and see that the bacteria in the colony all have a unstained capsule around them and you havent evolved the ability to break down the thick peptidoglycan yet.

But you did evolve the skill of horizontal gene transfer and could search for friendly bacteria close by that could share that ability with you.

up the ladder you evolve by symbiosis and might gain your first organelles that allow you to become light sensitive.

maybe this leads you to a path where you decide to use light as main energy source instead of other bacteria or cellular debris.

(post goes on in replies)
#gamedesign #science #research #biology

Do you remember the 2008? #game #spore that lets you play with #evolution starting as a #protozoa and you play to evolve to landfall and later space?

Like back then i still feel the only great part of this game is in fact the top down view playing your single celled organism, but i also feel it falls utterly short.

2008 was long before i became a #microscopy nerd and before i learned about #medical #microbiology .

What i love about microbiology and microscopy is that its such an alien world that allows for endless magical discovery. Where a single cell is alive and buzzing like a whole city with complex dynamics and the view through a microscope that looks visually just stunning and so vivid that no game #graphics can actually compete with it.

The game is there already, complex and alive, all around us.

Imagine a top down view just like the view through the microscope. Bright white background. you start as a single most basic bacterium. Invisible, of course. Here come different imaging and staining techniques into play.

Its an #RPG and you #levelup your bacterium. You eat, grow and evolve with a skill tree that reflects scientifically accurate abilities. evolve to break down cellulose for food, evolve a outer cell membrane and become a #grampositive bacterium for increased protection, evolve to build out spores so if you die you can get revived, evolve to build out a flagellum for motility and speed. (post goes on in replies)
#gamedesign #science #research #biology

I have a question about image processing. I took images with the same magnification and zoom. I rotated and cropped them in FIJI and added scale bars. The scale bar on one of the images is longer than the others. What is going on. I am literally about to lose it. I appreciate any advice.#microscopy #FIJI#science