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Giuseppe MichieliBeyond <a href="https://mstdn.science/tags/MERS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MERS</a>: <a href="https://mstdn.science/tags/Merbecovirus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Merbecovirus</a> <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> plasticity calls for emergence <a href="https://mstdn.science/tags/preparedness" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preparedness</a>, <a href="https://etidiohnew.blogspot.com/2025/04/beyond-mers-merbecovirus-receptor.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/04/beyond-mers-merbecovirus-receptor.html</a>

John Vaccaro (johniac)SciTech Chronicles. . . . . . . . .Mar 26th, 2025<a href="https://bit.ly/stc032625" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://bit.ly/stc032625</a><a href="https://mastodon.social/tags/xenoliths" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#xenoliths</a> <a href="https://mastodon.social/tags/volatiles" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#volatiles</a> <a href="https://mastodon.social/tags/subduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#subduction</a> <a href="https://mastodon.social/tags/models" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#models</a> <a href="https://mastodon.social/tags/spike" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spike</a> <a href="https://mastodon.social/tags/glycans" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#glycans</a> <a href="https://mastodon.social/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> <a href="https://mastodon.social/tags/low" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#low</a>-mutation #<a href="https://mastodon.social/tags/Yellowknife" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Yellowknife</a> <a href="https://mastodon.social/tags/linear" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#linear</a> <a href="https://mastodon.social/tags/dodecane" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dodecane</a> <a href="https://mastodon.social/tags/SAM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SAM</a> <a href="https://mastodon.social/tags/lipids" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lipids</a> <a href="https://mastodon.social/tags/Mesoscale" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Mesoscale</a> <a href="https://mastodon.social/tags/signature" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#signature</a> <a href="https://mastodon.social/tags/transport" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#transport</a> <a href="https://mastodon.social/tags/photolysis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#photolysis</a> <a href="https://mastodon.social/tags/replenishment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#replenishment</a> <a href="https://mastodon.social/tags/size" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#size</a> <a href="https://mastodon.social/tags/thickness" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#thickness</a>

Giuseppe MichieliAltered <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding <a href="https://mstdn.science/tags/specificity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#specificity</a> of <a href="https://mstdn.science/tags/gull" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#gull</a>-adapted <a href="https://mstdn.science/tags/H13" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H13</a> avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> viruses corresponds to their unique host preferences, <a href="https://etidiohnew.blogspot.com/2025/03/altered-receptor-binding-specificity-of.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/03/altered-receptor-binding-specificity-of.html</a>

Giuseppe MichieliA <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a>-infecting <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virus: <a href="https://mstdn.science/tags/clinical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#clinical</a> features, virus <a href="https://mstdn.science/tags/reassortment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#reassortment</a>, <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding affinity, and possible <a href="https://mstdn.science/tags/transmission" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#transmission</a> routes, <a href="https://etidiohnew.blogspot.com/2025/03/a-human-infecting-h10n5-avian-influenza.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/03/a-human-infecting-h10n5-avian-influenza.html</a>

Giuseppe MichieliStructural basis of <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding <a href="https://mstdn.science/tags/adaptation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#adaptation</a> of <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a>-infecting <a href="https://mstdn.science/tags/H3N8" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N8</a> <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> A virus, <a href="https://etidiohnew.blogspot.com/2025/02/structural-basis-of-receptor-binding.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/02/structural-basis-of-receptor-binding.html</a>

Giuseppe MichieliNewfound <a href="https://mstdn.science/tags/bat" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bat</a> <a href="https://mstdn.science/tags/virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#virus</a> that uses notorious <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> poses ‘<a href="https://mstdn.science/tags/spillover" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spillover</a>’ <a href="https://mstdn.science/tags/risk" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#risk</a>, <a href="https://www.nature.com/articles/d41586-025-00503-7" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.nature.com/articles/d41586-025-00503-7</a> The virus is related to the <a href="https://mstdn.science/tags/pathogen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#pathogen</a> that causes <a href="https://mstdn.science/tags/MERS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MERS</a> and capitalizes on the same ‘entry receptor’ used by <a href="https://mstdn.science/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SARS</a>-CoV-2.

Bytes EuropeDiabetes drugs may boost brain health but experts warn of risks <a href="https://www.byteseu.com/753882/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.byteseu.com/753882/</a> <a href="https://pubeurope.com/tags/Addiction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Addiction</a> <a href="https://pubeurope.com/tags/Anxiety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Anxiety</a> <a href="https://pubeurope.com/tags/Brain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Brain</a> <a href="https://pubeurope.com/tags/CognitiveFunction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CognitiveFunction</a> <a href="https://pubeurope.com/tags/dementia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dementia</a> <a href="https://pubeurope.com/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://pubeurope.com/tags/diabetes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#diabetes</a> <a href="https://pubeurope.com/tags/Drugs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Drugs</a> <a href="https://pubeurope.com/tags/GLP1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GLP1</a> <a href="https://pubeurope.com/tags/Glucagon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Glucagon</a> <a href="https://pubeurope.com/tags/GlucagonLikePeptide1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GlucagonLikePeptide1</a> <a href="https://pubeurope.com/tags/Health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Health</a> <a href="https://pubeurope.com/tags/Inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Inflammation</a> <a href="https://pubeurope.com/tags/Insulin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Insulin</a> <a href="https://pubeurope.com/tags/MentalHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MentalHealth</a> <a href="https://pubeurope.com/tags/Metabolism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Metabolism</a> <a href="https://pubeurope.com/tags/Obesity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Obesity</a> <a href="https://pubeurope.com/tags/Preclinical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Preclinical</a> <a href="https://pubeurope.com/tags/Receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Receptor</a> <a href="https://pubeurope.com/tags/Research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Research</a> <a href="https://pubeurope.com/tags/Schizophrenia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Schizophrenia</a> <a href="https://pubeurope.com/tags/stress" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#stress</a>

CellBioNewsA blueprint for making <a href="https://scientificnetwork.de/tags/cereal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cereal</a> <a href="https://scientificnetwork.de/tags/crops" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#crops</a> more resistant to <a href="https://scientificnetwork.de/tags/fungal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#fungal</a> <a href="https://scientificnetwork.de/tags/disease" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#disease</a>.<a href="https://scientificnetwork.de/tags/agriculture" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#agriculture</a> <a href="https://scientificnetwork.de/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#immune</a> <a href="https://scientificnetwork.de/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> <a href="https://scientificnetwork.de/tags/MLA13" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MLA13</a> <a href="https://scientificnetwork.de/tags/AVRA13" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AVRA13</a>-1 <a href="https://scientificnetwork.de/tags/powdery_mildew" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#powdery_mildew</a> <a href="https://phys.org/news/2025-02-blueprint-cereal-crops-resistant-fungal.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2025-02-blueprint-cereal-crops-resistant-fungal.html</a>

Giuseppe MichieliStructure of a <a href="https://mstdn.science/tags/zoonotic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#zoonotic</a> <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a> <a href="https://mstdn.science/tags/hemagglutinin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hemagglutinin</a> reveals a <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding site occupied by an auto-glycan, <a href="https://etidiohnew.blogspot.com/2025/01/structure-of-zoonotic-h5n1.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/01/structure-of-zoonotic-h5n1.html</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/Receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Receptor</a> <a href="https://mstdn.science/tags/binding" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#binding</a>, <a href="https://mstdn.science/tags/structure" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#structure</a>, and <a href="https://mstdn.science/tags/tissue" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tissue</a> <a href="https://mstdn.science/tags/tropism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tropism</a> of <a href="https://mstdn.science/tags/cattle" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cattle</a>-infecting <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a> avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virus <a href="https://mstdn.science/tags/hemagglutinin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hemagglutinin</a>, <a href="https://etidiohnew.blogspot.com/2025/01/receptor-binding-structure-and-tissue.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/01/receptor-binding-structure-and-tissue.html</a>

Bytes EuropeResearchers create an atlas of health associations for GLP-1 receptor agonists <a href="https://www.byteseu.com/670258/" rel="nofollow noopener noreferrer" target="_blank">https://www.byteseu.com/670258/</a> <a href="https://pubeurope.com/tags/AbdominalPain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AbdominalPain</a> <a href="https://pubeurope.com/tags/alcohol" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#alcohol</a> <a href="https://pubeurope.com/tags/Anemia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Anemia</a> <a href="https://pubeurope.com/tags/Cardiometabolic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Cardiometabolic</a> <a href="https://pubeurope.com/tags/Chronic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Chronic</a> <a href="https://pubeurope.com/tags/diabetes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#diabetes</a> <a href="https://pubeurope.com/tags/DiabetesMellitus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DiabetesMellitus</a> <a href="https://pubeurope.com/tags/Drugs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Drugs</a> <a href="https://pubeurope.com/tags/Efficacy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Efficacy</a> <a href="https://pubeurope.com/tags/GLP1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GLP1</a> <a href="https://pubeurope.com/tags/Health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Health</a> <a href="https://pubeurope.com/tags/Hypotension" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hypotension</a> <a href="https://pubeurope.com/tags/Kidney" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Kidney</a> <a href="https://pubeurope.com/tags/Medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Medicine</a> <a href="https://pubeurope.com/tags/Musculoskeletal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Musculoskeletal</a> <a href="https://pubeurope.com/tags/nausea" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nausea</a> <a href="https://pubeurope.com/tags/Obesity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Obesity</a> <a href="https://pubeurope.com/tags/Pain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Pain</a> <a href="https://pubeurope.com/tags/Pneumonia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Pneumonia</a> <a href="https://pubeurope.com/tags/Receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Receptor</a> <a href="https://pubeurope.com/tags/Research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Research</a> <a href="https://pubeurope.com/tags/Respiratory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Respiratory</a> <a href="https://pubeurope.com/tags/semaglutide" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#semaglutide</a> <a href="https://pubeurope.com/tags/Sleep" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Sleep</a> <a href="https://pubeurope.com/tags/stroke" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#stroke</a> <a href="https://pubeurope.com/tags/Type2Diabetes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Type2Diabetes</a> <a href="https://pubeurope.com/tags/Vomiting" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Vomiting</a>

Giuseppe MichieliGGCX promotes <a href="https://mstdn.science/tags/Eurasian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Eurasian</a> <a href="https://mstdn.science/tags/avian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#avian</a>-like <a href="https://mstdn.science/tags/H1N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H1N1</a> <a href="https://mstdn.science/tags/swine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#swine</a> <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virus <a href="https://mstdn.science/tags/adaption" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#adaption</a> to interspecies <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> binding, <a href="https://etidiohnew.blogspot.com/2025/01/ggcx-promotes-eurasian-avian-like-h1n1.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/01/ggcx-promotes-eurasian-avian-like-h1n1.html</a>

Giuseppe MichieliThe <a href="https://mstdn.science/tags/Haemagglutinin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Haemagglutinin</a> <a href="https://mstdn.science/tags/Gene" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Gene</a> of <a href="https://mstdn.science/tags/Bovine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bovine</a>-Origin <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a> <a href="https://mstdn.science/tags/Influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Influenza</a> Viruses Currently Retains <a href="https://mstdn.science/tags/Receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Receptor</a>-binding and pH-fusion Characteristics of <a href="https://mstdn.science/tags/Avian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Avian</a> <a href="https://mstdn.science/tags/Host" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Host</a> Phenotype, <a href="https://etidiohnew.blogspot.com/2025/01/the-haemagglutinin-gene-of-bovine.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/01/the-haemagglutinin-gene-of-bovine.html</a>

Giuseppe MichieliRandom forest <a href="https://mstdn.science/tags/algorithm" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#algorithm</a> reveals novel sites in <a href="https://mstdn.science/tags/HA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HA</a> <a href="https://mstdn.science/tags/protein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#protein</a> that shift <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> binding preference of the <a href="https://mstdn.science/tags/H9N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H9N2</a> avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virus, <a href="https://etidiohnew.blogspot.com/2025/01/random-forest-algorithm-reveals-novel.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/01/random-forest-algorithm-reveals-novel.html</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/Structure" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Structure</a> of a <a href="https://mstdn.science/tags/zoonotic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#zoonotic</a> <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a> <a href="https://mstdn.science/tags/hemagglutinin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hemagglutinin</a> reveals a <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding site occupied by an auto-glycan, BioRxIV: <a href="https://www.biorxiv.org/content/10.1101/2024.12.06.626699v1?rss=1" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.biorxiv.org/content/10.1101/2024.12.06.626699v1?rss=1</a> We found that receptor-binding site of this H5N1 hemagglutinin was already occupied by an 2-3-linked sialic acid and that this glycan emanated from asparagine N169 of a neighboring protomer on hemagglutinin itself.

Giuseppe MichieliDual <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding, <a href="https://mstdn.science/tags/infectivity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infectivity</a>, and <a href="https://mstdn.science/tags/transmissibility" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#transmissibility</a> of an emerging <a href="https://mstdn.science/tags/H2N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H2N2</a> low pathogenicity avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virusSource: Nature Communications, AbstractThe 1957 H2N2 influenza pandemic virus has disappeared from humans since 1968, while H2N2 avian influenza viruses (AIVs) are still circulating in birds. It is necessary to reveal the recurrence risk and potential cross-species infection of these AIVs from avian to mammals. We find that H2 AIVs circulating in…<a href="https://etidioh.wordpress.com/2024/11/20/dual-receptor-binding-infectivity-and-transmissibility-of-an-emerging-h2n2-low-pathogenicity-avian-influenza-virus/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidioh.wordpress.com/2024/11/20/dual-receptor-binding-infectivity-and-transmissibility-of-an-emerging-h2n2-low-pathogenicity-avian-influenza-virus/</a>

Giuseppe MichieliStructural basis for <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding domain mobility of the <a href="https://mstdn.science/tags/spike" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spike</a> in <a href="https://mstdn.science/tags/SARS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SARS</a>-CoV-2 <a href="https://mstdn.science/tags/BA286" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BA286</a> and <a href="https://mstdn.science/tags/JN1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#JN1</a>Source: Nature Communications, AbstractSince 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the up-conformation. However, whether ACE2 also interacts with the RBD in the down-conformation to…<a href="https://etidioh.wordpress.com/2024/10/07/structural-basis-for-receptor-binding-domain-mobility-of-the-spike-in-sars-cov-2-ba286-and-jn1/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidioh.wordpress.com/2024/10/07/structural-basis-for-receptor-binding-domain-mobility-of-the-spike-in-sars-cov-2-ba286-and-jn1/</a>

Giuseppe MichieliTheoretical <a href="https://mstdn.science/tags/Investigations" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Investigations</a> of a point <a href="https://mstdn.science/tags/mutation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mutation</a> affecting <a href="https://mstdn.science/tags/H5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5</a> <a href="https://mstdn.science/tags/HA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HA</a>’s <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> binding preference, Comput Biol Chem.: <a href="https://www.sciencedirect.com/science/article/abs/pii/S1476927124001774?via%3Dihub" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.sciencedirect.com/science/article/abs/pii/S1476927124001774?via%3Dihub</a> <a href="https://mstdn.science/tags/D94N" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#D94N</a> <a href="https://mstdn.science/tags/mutation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mutation</a> on HA causes a shift in receptor binding preference from <a href="https://mstdn.science/tags/avian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#avian</a>-type SAα2,3Gal to <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a>-type SAα2,6Gal. Mutation causes an enhanced flexibility of the 130-Loop, leading to instability of HA-SAα2,3Gal complex. Resilience of interactions between HA & SAα2,6Gal is attributed to the inherent flexibility of glycan.

CellBioNewsScientists discover novel <a href="https://scientificnetwork.de/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> recognition mechanism for <a href="https://scientificnetwork.de/tags/alphavirus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#alphavirus</a>.<a href="https://scientificnetwork.de/tags/Eastern_Equine_Encephalitis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Eastern_Equine_Encephalitis</a> <a href="https://scientificnetwork.de/tags/VLDLR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#VLDLR</a> <a href="https://phys.org/news/2024-08-scientists-receptor-recognition-mechanism-alphavirus.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2024-08-scientists-receptor-recognition-mechanism-alphavirus.html</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/Structure" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Structure</a> defining of ultrapotent neutralizing <a href="https://mstdn.science/tags/nanobodies" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nanobodies</a> against <a href="https://mstdn.science/tags/MERS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MERS</a>-CoV with novel epitopes on <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a> binding domain <a href="https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012438" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012438</a> These results not only character unprecedented epitopes for antibody recognition but also provide promising agents for prophylaxis and therapy of MERS-CoV infection.

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