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In pharmacology, an #antidepressant refers to a fairly diverse set of molecules that do not have the same modes of action, the same therapeutic effects or the same undesirable effects.
A common goal: to target monoamines, neuromodulators
Generally speaking, these are molecules that target what are called #neurotransmitters, including serotonin, noradrenaline or dopamine. When a neurotransmitter attaches to receptors in one neuron, it transmits an electrical message that can be transmitted to another neuron. It's kind of like a relay race. There are over 20 different types of synapses, each of which conveys specific messages and are involved in this brain activity differently."
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#Antidepressants "change your perception of the world, the kinetics of your movements or your emotional reactivity.
"Several studies have shown that very early changes (before any effect on mood) affect the recognition of facial emotions, the learning of new information or the updating of your beliefs."
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"When you take an antidepressant, it is easier for you to recognize the smiles, the positive feelings on the faces of the people you're meeting on the street. It also is harder for you to recognize the negative feelings, the feelings of anger, the feelings of fear. And you have an easier recall of your positive, pleasant memories of the past.
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Reference in French: https://www.radiofrance.fr/franceculture/podcasts/votre-cerveau/ep5-comment-les-antidepresseurs-corrigent-vos-biais-cognitifs-3339139
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"In depression, movement slows down, speech becomes very rare. Immobility gradually spreads to the body. After a week of antidepressant therapy, you can see a relief of this motor inhibition, as if the movements had regained their amplitude, their kinetics, the muscles were awakening and the tone returned.
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"This release of inhibition is also infamous in psychiatry, because it may temporarily increase the risk of suicide. If you have a death wish that is very powerful, but you no longer have any will, it will be very difficult for you to finally put your thoughts into action."
Reference in French: https://www.radiofrance.fr/franceculture/podcasts/votre-cerveau/ep5-comment-les-antidepresseurs-corrigent-vos-biais-cognitifs-3339139