#DMT #history #IndigenousKnowledge
"So, not only was ayahuasca powered by DMT, but was also, as William Burroughs had speculated, a true pharmacological technology, exploiting the synergistic interaction between the constituent harmala and tryptamine alkaloids.
Naturally, this immediately raised questions as to how the Indigenous peoples of South America, without any knowledge of the underlying biochemistry, could possibly have discovered, from the tens of thousands of plant species that filled the rain forests, that combining this particular pair of plants, neither of which produced any significant psychoactive effects when consumed orally alone, would elicit one of the most profound visionary experiences produced by any substance.
It seemed almost miraculous in its implausibility, with ethnobotanist Jonathan Ott later calling it 'conceivably the most sophisticated pharmacognostical discovery ever made in the archaic world.'
Since some groups still prepare a decoction using the caapi vine alone—with limited visionary effects—it’s likely that this potent synergistic combination was discovered after a long period of trial and error, with different plants added and tested over perhaps hundreds of years. Eventually, the minimal binary decoction of the caapi vine plus chacruna or chacropanga was discovered.
This in no way detracts from the brilliance of the discovery, but if anything, demonstrates the Indigenous people’s tenacity in developing this technology over many centuries, such was its value in making the Hidden Ones visible. A technology of this importance was worth the effort."
https://lithub.com/natures-strangest-psychedelic-is-everywhere-the-ever-surprising-history-of-dmt/