Let's also consider #Gigantopithecus, the largest ape in history, as an example of human-like anatomy in a very large, legitimately bipedal structure.
Estimates of Gigantopithecus range from 2.7 to 3.7 meters, well over that 2.5 m I was talking about with humans, and this is the average height for a species, meaning we know it must be stable because otherwise evolution would have selected against it. Gigantopithecus is believed to have gone extinct due to changing environmental factors, which means it might have been sensitive to environment, but that is less of a concern if we are just talking about whether something that size can be healthy.
Combining our knowledge of these species, and what makes humans unhealthy at that height, we get a picture of a human that is not simply tall, but wide, perhaps very wide, so that the legs can easily support that weight and a lot of organ mass can be held up in the midsection.
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