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#genomics

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If there is any sort of lesson to be learnt from this its that #genomics data will often throw up ‘edge cases’ that will confound your well-reasoned attempt to write some #bioinformatics code to process large datasets.

The fewer assumptions you make about what your data might look like, the better!

Whenever I see a DNA logo from a lab, bioinformatics/genomics centre, hackathon, or training course and it’s backwards I sigh a little. I don’t point them out anymore as I usually just receive passive aggression, but what does it say about you that you don’t care? Several big ones in my stream today. If an entomology training centre had a logo with an 8-legged fly it’d be weird right? #bioinformatics #genomics #DNA

**Megatrend #12** - Personalized, Precision Medicine: "Tomorrow's cure lies not in a universal pill, but within our own genetic code." - Futurist Jim Carroll

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(Futurist Jim Carroll is writing a series on 30 Megatrends, which he first outlined in his book Dancing in the Rain: How Bold Leaders Grow Stronger in Stormy Times. The trends were shared in the book as a way of demonstrating that, despite any period of economic volatility, there is always long-term opportunity to be found. The book is now in print - learn more at dancing.jimcarroll.com)

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The one-size-fits-all era in medicine is ending. Treatments, nutrition, and wellness approaches tailored to individual genetic profiles are becoming the standard, not the exception. As with every post in this series, there's a PDF here that goes into more depth on this trend.

There's a little bit of duplication with some of the material covered in previous megatrends with this one, but it's important ot note that this trend is powerful enough on its own to deserve its own post.

What's it all about? We are combining what we might call 'next-generation genomic sequencing', AI, and CRISPR gene editing, to come up with a new health paradigm that involves 'fixing people before they are sick rather than after.' Why these 3 trends? The cost for genomic sequencing is collapsing, AI is accelerating the ability to do so, and gene editing allows us to correct the genetic causes of disease at the source.

Before going further, it's important to define the revolution by understanding two key terms.

The first is Personalized Medicine, which uses an individual's unique genomic, environmental, and lifestyle information to guide decisions for prevention, diagnosis, and treatment of disease. It's based on the idea that because no two individuals are the same, they should not receive the same healthcare.

The second term is Precision Medicine. While often used interchangeably, it more accurately describes the strategy of stratifying individuals into small populations based on shared characteristics. It focuses on identifying which healthcare and pharmaceutical approaches will be most effective for those small, specific groups of people, rather than creating unique treatments for each individual.

While its potential is immense, the transition to personalized medicine is not merely a technological upgrade but a disruptive force that challenges the foundational structures of healthcare delivery, research, and regulation.

Even so, over the long term, it's one of the biggest megatrend opportunities of our time.

**#Personalized** **#Medicine** **#Genomics** **#CRISPR** **#AI** **#Precision** **#Healthcare** **#Genetics** **#Innovation** **#Future**

Original post: jimcarroll.com/2025/07/decodin

**Megatrend #10** — Predictive and Preventative Healthcare:
“𝑇ℎ𝑒 𝑚𝑒𝑑𝑖𝑐𝑖𝑛𝑒 𝑜𝑓 𝑡𝑜𝑚𝑜𝑟𝑟𝑜𝑤 𝑖𝑠𝑛’𝑡 𝑎𝑏𝑜𝑢𝑡 𝑡ℎ𝑒 𝑚𝑖𝑟𝑎𝑐𝑙𝑒 𝑐𝑢𝑟𝑒; 𝑖𝑡’𝑠 𝑎𝑏𝑜𝑢𝑡 𝑡ℎ𝑒 𝑝𝑟𝑒𝑑𝑖𝑐𝑡𝑖𝑣𝑒 𝑖𝑛𝑠𝑖𝑔ℎ𝑡 𝑡ℎ𝑎𝑡 𝑚𝑎𝑘𝑒𝑠 𝑡ℎ𝑒 𝑐𝑢𝑟𝑒 𝑢𝑛𝑛𝑒𝑐𝑒𝑠𝑠𝑎𝑟𝑦.” — Futurist Jim Carroll

Medicine is shifting from reactive treatment to anticipatory care through continuous monitoring, AI diagnostics, and early intervention. We are moving from fixing people after they are sick to knowing what they will become sick with and acting accordingly. This creates fundamentally different business models across the health system and massive new business and societal opportunities.

The interesting thing about this trend is that while it involves so much promise, it also requires societies that have a mature relationship with science and the future. Given some of the recent events throughout the US, it is becoming obvious that other parts of the world will see greater advancements with this megatrend.

With that in mind, let's dive into the idea of "health reimagined.". Want the full report? There's a PDF here!

pdf.jimcarroll.com/Megatrend10

What's underneath it all are four major trends that form the central nervous system of a proactive health ecosystem.

Artificial Intelligence: The engine of the proactive health revolution, enabling risk prediction, diagnostic enhancement, and personalized care at an unprecedented scale.

Genomics: The biological blueprint for personalized medicine, enabling a shift from population averages to truly individualized care.

Wearables & IoMT: The continuous monitoring network that captures real-time physiological and behavioral data in everyday life.

Data Interoperability: The connective tissue that enables seamless information flow across the entire health ecosystem.

Will all of this happen?

There's a lot of pie-in-the-sky thinking that involves huge change with a massively complex system. Some societies are no longer mature enough to chase the opportunities.

But the trends, technology, and science identified above are evolving at an astonishing speed, and so clearly, this is a megatrend to watch.

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Futurist Jim Carroll has been covering the trends in this article throughout the global healthcare sector for 20+ years. More details can be found at
healthcare.jimcarroll.com

**#Healthcare** **#Predictive** **#AI** **#Genomics** **#Wearables** **#Prevention** **#Personalized** **#Medicine** **#Innovation** **#Future**

Original post: jimcarroll.com/2025/07/decodin